Experienced vascular anomalies specialists can make the correct diagnosis based on the history, clinical presentation, and appearance of the vascular anomaly. Testing may include blood tests, ultrasound, x-ray, MRI, lymphoscintigram, eye examination by an ophthalmologist, bronchoscopy, endoscopy, etc., depending on the location or characteristics of the vascular anomaly. The most frequently ordered diagnostic tests are listed in the Table 3. Typically, photographs will be taken at each visit to document the changes (including response to treatment, if pertinent) in the vascular anomaly over time.
Sometimes the diagnosis is not clear. A biopsy may be required if there is any question of the diagnosis and histologic confirmation is required.