BCG is administered through a catheter. The nurse will ask you to urinate to empty your bladder completely. A urine dipstick test will be performed to test for blood or infection. If the dipstick test is negative, then the BCG will be instilled into your bladder through the catheter. Once the solution is in your bladder, the catheter will be removed, leaving the solution in your bladder. It is best to hold the medication in your bladder for about 2 hours. After 2 hours, you will urinate normally into a toilet (not outside or into an outhouse). Immediately flush the toilet and wash your hands.
The treatment course for BCG varies depending on the details of the individual tumor. A typical course is given once a week for 6 weeks, and then the cystoscopy exam is repeated. If the tumor has been eradicated, no further BCG is usually given at that time. Recurrent tumors are usually removed again by a TURBT. A second course of BCG may be given after this, with continued treatments possible in many cases.