Yes, particularly estrogen-containing compounds. In addition to Tamoxifen, using estrogen replacement therapy can increase the risk of uterine cancer. This is why, if used, it is given with progesterone, which is another female hormone that usually helps to support a pregnancy. Progesterone is included in combined hormonal preparations and is required to reduce the risk of uterine cancer in susceptible women. Beyond hormonally-acting agents, there are no other medications linked with the diagnosis of uterine cancer.